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Oxanabol is a steroid with low anabolic activity, stimulating the synthesis of creatine phosphate in muscle cells, which contributes to the increase in strength indicators . A metabolite of testosterone called dihydrotestosterone has been reported to increase a muscle's strength. The mechanism of its increase is unclear, but it is speculated that a stimulation of protein catabolism and/or direct action of anabolic hormones from the liver (which also increase muscle size) can help to increase the metabolic rate and to produce more creatine phosphate for more synthesis of creatine and for the greater retention of strength in a muscle  . Another study that has been reported to stimulate growth of muscle tissue, with moderate anabolic activity but low anabolic activity, was a 20 week trial in subjects with idiopathic skeletal muscle wasting, that involved either a combination of oral (100–800mg) testosterone (1% for an average of 6 weeks) with a hydrochloric acid solution (1% for an average of 6 weeks) or a placebo (0, 2% sodium chloride for an average of 6 weeks) given in pill form for 20 weeks  . While the dose of testosterone used was slightly higher than is commonly used in older men  , the combination with the use of the active hormone was found to increase the amount of protein synthesis in muscle that would not have otherwise had occurred if only testosterone had been given  . Some studies of other anabolic steroids have reported significant increases in muscle size in subjects with lower testosterone levels. In one study, a high dose of testosterone enanthate (50, 100, 200mg/day) in 8-week-old male Sprague-Dawley rats (0.5–2.25mmol/L) for 4 weeks with a 3-week washout period resulted in an increase in the size of triceps surae muscle that was 1.4mm larger at 4 weeks than before the intervention started, and a 2.5-mm increase at 8 weeks in muscle fiber fractional anaerobically-induced anagen  . In two other studies, rats treated with testosterone (30, 70, 100 mg/day) for 2 weeks with a washout period at 15 weeks showed similar results, with 5.2% of the rats showing a 2.9% total increase (5.7% to 6.3%) in mass as compared to 3.8% before the intervention began. The increase in muscle mass was greatest in males with higher circulating testosterone levels  . The increase in muscle size observed in the study of Vaisman et Similar articles: